Plasmid Products Highlights
uBriGene has well-established plasmid libraries, including human ORF cDNA clone library, human microRNA clone library, human shRNA clone library, human gRNA pool clone library, and mouse gRNA pool clone library. We feature a large quantity and a wide variety of high-quality products with short delivery time. Our ready-for-use GMP Plasmids have the following advantages:
GMP grade plasmids can be modified to satisfy customized applications
Stable and traceable supply
DMF registration number available, which can be directly used for IND application
Great time and production costs reduction; experienced for multiple orders of lentivirus and CAR-T cell therapy
Independent intellectual property rights
Why is a three-tiered cell bank required?According to regulations, a complete culture cell bank must be established before GMP-grade plasmid production, including the primary cell bank, the master cell bank and the working cell bank.
What is the storage temperature for plasmids? How long can they be stored?According to BriGene’s many years of GMP plasmid production experience, the storage temperature of plasmids is -20°C, and the long-term storage stability data can be traced back for more than half a year.
Which strain is used to produce plasmids?uBriGene uses DH5α or Stbl3 for plasmid production, depending on the customer's choice.
Why are plasmids modified for kanamycin resistance?Regulations require that the vectors used in gene therapy drugs must not introduce resistance to penicillin.
Gene of Interest
IIT non-registered clinical study / investigational new drug (IND) application / gene therapy commercialization