To study gene functions, genes are usually inserted or knocked out in a particular cell or organism. The changes in cellular biological activities or organism inherited phenotypic traits are observed, which are two main research strategies, gain of function or inactivation. 

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Besides various helper plasmids and serotype plasmids for lentivirus and AAV packaging, uBriGene also offers plasmid engineering and manufacturing services including gene overexpression, gene silencing, and CRISPR/Cas9 knockouts. Special plasmid sequence design and vector construction, e.g. shRNA plasmids and target gene templates, are also provided based on client’s needs to achieve modifications on different functional components. 

With over a decade of experience in plasmid production and development, uBriGene leads the industry by providing high-quality plasmid preparation services tailored to meet the needs of our customers. Our expertise extends to our patented AAV helper plasmids, customized AAV vectors, plasmid cloning and expression, and CRIPSR plasmids for precise gene editing.