To study gene functions, genes are usually inserted or knocked out in a particular cell or organism. The changes in cellular biological activities or organism inherited phenotypic traits are observed, which are two main research strategies, gain of function or inactivation. 

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Besides various helper plasmids and serotype plasmids for lentivirus and AAV packaging, uBriGene also offers plasmid construction services including gene overexpression, gene silencing, CRISPR/Cas9 knockouts etc. Special plasmid sequence design and vector construction are also provided based on client’s needs to achieve modifications on different functional components.